Fetal Bovine Serum

Cell culture

Fetal Bovine Serum from different countries of origins is sterile filtered and quality tested.

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MSDS FBS Good MSDS FBS Good MSDS FBS Tetracyclin free MSDS FBS Tetracyclin free Product catalogue Pan Biotech

PAN-Biotech offers special types of serum: charcoal absorbed, delipidized, dialyzed, gamma irradiated, heat inactivated and gamma globulin reduced.

Fetal bovine serum, EU approved, tetracycline free

Tetracycline-free serum

Fetal bovine serum is tested for absence of tetracycline using the TET-off system (luciferase).

Application

• TET-on / TET-off regulated gene expression
• Transfections
• Expression studies

FBS Good

FBS Good is created as a naturally defined serum with a sustained growth promoting property and a higher safety. FBS Good only contains serum of highest quality from defined countries as specified. It is not blended or enhanced by addition of growth factors or proteins.

FBS Good advantages

Reproducible growth properties
Very low endotoxin level
Suitable for a great variety of cells
Continuous quality control

Heat inactivated serum

Serum is heated for 30 min to 56 °C in a water bath under repeated gentle mixing.

Application

• Measurements of lactate dehydrogenase in the culture supernatant as a marker for cell damage (serum LDH is inactivated by heat)
• Minimizes lot-to-lot variations in serum (all thermolabile components are removed)
• Studies on vitamins and growth factors
• Enhance viral safety, since heat-labile viruses are inactivated
• Tests that do not tolerate presence of complement (complement destruction).

Quality

All serum processing steps take place in PAN-Biotech's own production facilities in Aidenbach/Germany. Pooling, sterile filtration and aseptic filling take place in clean room atmospheres set up according to GMP guidelines. Raw material is obtained exclusively from facilities listed in the European Union TRACES system.

PAN-Biotech warrants the submission of a complete documentation, consisting of a certificate of origin and a veterinary certificate, shipping documents and a certificate of analysis. Furthermore, every single procedure during an individual production process is documented and then summarized in a production protocol.

The function of serum in cell cultures

Stimulates cell growth, proliferation and differentiation through hormonal factors
Adhesion factors facilitate and enhance cell attachment on culture dishes (bio-matrix)
Transport and binding proteins provide hormones, minerals and lipids
Inhibition of toxic substances by binding to serum proteins

Advantages of PAN-Biotech

Own raw material resources in different countries
Certified according to DIN ISO 9001:2008 and EN ISO 13485:2012
Certificate of Suitability (COS) no. R1-CEP 2002-167-Rev 00
Licensed according to the EU-decree no. 1774/2002 with vet. no. DE 09 275 0001 14
Every single batch is fully documented and traceable – from the country of origin to the end product
We offer special types of serum: charcoal absorbed, delipidized, dialyzed, gamma irradiated, heat inactivated and gamma globulin reduced
Highest production and safety standards for serum manufacturing
Best references from industry and research
Extensive analyses and tests are presented in Certificate of Analysis (CoA)

Product	Description
Fetal bovine serum	Australia origin, 100 ml or 500 ml
Fetal bovine serum	South Africa origin, 100 ml or 500 ml
Fetal bovine serum	South America origin, 100 ml or 500 ml
Fetal bovine serum	US admissible, 100 ml or 500 ml
Fetal bovine serum	US origin, 100 ml or 500 ml